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The RCEM position statement November 2021 recommended that the use of the SNAP regime to treat paracetamol toxicity should become the default standard practise in all emergency departments. Prior to this uptake of the SNAP regime had been sporadic across the UK with some early adopter sites utilising in place of the previous 21hr standard 3 bag protocol with the benefit of a reduced length of NAC treatment.
As per the Lancet publication 2019, The SNAP regime has been shown to be as effective as the traditional regime in preventing liver injury, with fewer adverse reactions (anaphylactoid reactions). www.piernetwork.org/paracetamol-overdose-snap-protocol.html
The SNAP protocol has been developed at HHFT and is available in a simple 2 page protocol. This can be downloaded from the guideline page.
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